Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.
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| Format: | conferenceObject |
| Language: | eng |
| Published: |
2023
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| Online Access: | http://hdl.handle.net/11086/547807 |
| _version_ | 1806012043084431360 |
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| author | Cabrera Zapata, Lucas Ezequiel Cambiasso, María Julia |
| author_facet | Cabrera Zapata, Lucas Ezequiel Cambiasso, María Julia |
| author_sort | Cabrera Zapata, Lucas Ezequiel |
| collection | Repositorio Digital Universitario |
| description | Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. |
| format | conferenceObject |
| id | rdu-unc.547807 |
| institution | Universidad Nacional de Cordoba |
| language | eng |
| publishDate | 2023 |
| record_format | dspace |
| spelling | rdu-unc.5478072024-07-02T18:28:12Z Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro Cabrera Zapata, Lucas Ezequiel Cambiasso, María Julia Estradiol Calcium Hypothalamic Diseases Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Fil: Cabrera Zapata, Lucas Ezequiel. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina. Fil: Cambiasso, María Julia. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra de Biología Celular B; Argentina. Fil: Cambiasso, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Estrogens generate a wide diversity of rapid “non-classical” effects which occur in a range from some seconds to few minutes (Arevalo et al., 2012), including the triggering of Ca2+ signals (Wong et al., 2012) and the activation of several signaling pathways such as the protein kinase C (PKC) and the extracellular signal-regulated kinase 1 and 2 (ERK1/2) cascades (Wu et al., 2005). Previous studies from our laboratory have shown that 17β-estradiol (E2) induces axonal growth through ERK1/2 activation in hypothalamic neurons of male embryos of 16 days of gestation (E16; Gorosito & Cambiasso, 2008). Both axogenesis and ERK1/2 activation mediated by the hormone depend on Ca2+ and Ca2+- dependent PKC isoforms (Gorosito & Cambiasso, 2008).In the present study we investigate the Ca2+ pools that participate in the activation of ERK1/2 and axogenesis by E2. http://falan-ibrolarc.org/drupal/es/content/scientific-programme Fil: Cabrera Zapata, Lucas Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Fil: Cabrera Zapata, Lucas Ezequiel. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina. Fil: Cambiasso, María Julia. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra de Biología Celular B; Argentina. Fil: Cambiasso, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Bioquímica y Biología Molecular (ídem 3.1.10) 2023-06-16T12:15:21Z 2023-06-16T12:15:21Z 2016 conferenceObject http://hdl.handle.net/11086/547807 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso; Electrónico y/o Digital |
| spellingShingle | Estradiol Calcium Hypothalamic Diseases Cabrera Zapata, Lucas Ezequiel Cambiasso, María Julia Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title | Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title_full | Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title_fullStr | Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title_full_unstemmed | Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title_short | Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| title_sort | activation of erk1 2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro |
| topic | Estradiol Calcium Hypothalamic Diseases |
| url | http://hdl.handle.net/11086/547807 |
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