Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings.
2 p.
| Main Authors: | , , , , , , |
|---|---|
| Other Authors: | |
| Format: | publishedVersion |
| Language: | eng |
| Published: |
2025
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11086/556625 |
| _version_ | 1839027527674232832 |
|---|---|
| author | Leathers, James S. Pisano, María Belén Ré, Viviana Elizabeth van Oord, G. Sultan, A. Boonstra, A. Debes, J. D. |
| author2 | https://orcid.org/0000-0002-0336-3750 |
| author_facet | https://orcid.org/0000-0002-0336-3750 Leathers, James S. Pisano, María Belén Ré, Viviana Elizabeth van Oord, G. Sultan, A. Boonstra, A. Debes, J. D. |
| author_sort | Leathers, James S. |
| collection | Repositorio Digital Universitario |
| description | 2 p. |
| format | publishedVersion |
| id | rdu-unc.556625 |
| institution | Universidad Nacional de Cordoba |
| language | eng |
| publishDate | 2025 |
| record_format | dspace |
| spelling | rdu-unc.5566252025-07-28T11:13:44Z Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. Leathers, James S. Pisano, María Belén Ré, Viviana Elizabeth van Oord, G. Sultan, A. Boonstra, A. Debes, J. D. https://orcid.org/0000-0002-0336-3750 Hepatitis C Rapid Diagnostic Test Resource Limited Hepacivirus 2 p. publishedVersion Fil: Leathers, James S. Vanderbilt University; Estados Unidos. Fil: Pisano, María Belén. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología "Dr. J.M. Vanella"; Argentina. Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología "Dr. J.M. Vanella"; Argentina. Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: van Oord, Gertine. Erasmus Medical Center; Países Bajos. Fil: Sultan, Amir. Addis Ababa University; Etiopía. Fil: Boonstra, Andre. Erasmus Medical Center; Países Bajos. Fil: Debes, José D. Universidad de Minnesota; Estados Unidos. Background: Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradication worldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usually constrained by testing costs. Methods: We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141 individuals. Results: The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotype or viral load (in samples with such information, 90%). Conclusions: The HCV test validated in this study can allow for HCV screening in areas of need when properly used. publishedVersion Fil: Leathers, James S. Vanderbilt University; Estados Unidos. Fil: Pisano, María Belén. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología "Dr. J.M. Vanella"; Argentina. Fil: Pisano, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: Ré, Viviana Elizabeth. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología "Dr. J.M. Vanella"; Argentina. Fil: Ré, Viviana Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: van Oord, Gertine. Erasmus Medical Center; Países Bajos. Fil: Sultan, Amir. Addis Ababa University; Etiopía. Fil: Boonstra, Andre. Erasmus Medical Center; Países Bajos. Fil: Debes, José D. Universidad de Minnesota; Estados Unidos. Enfermedades Infecciosas 2025-07-25T19:08:52Z 2025-07-25T19:08:52Z 2019 article 1876-3405 doi:10.1093/inthealth/ihy101 http://hdl.handle.net/11086/556625 1876-3405 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso; Electrónico y/o Digital |
| spellingShingle | Hepatitis C Rapid Diagnostic Test Resource Limited Hepacivirus Leathers, James S. Pisano, María Belén Ré, Viviana Elizabeth van Oord, G. Sultan, A. Boonstra, A. Debes, J. D. Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title | Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title_full | Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title_fullStr | Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title_full_unstemmed | Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title_short | Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings. |
| title_sort | validation of a point of care rapid diagnostic test for hepatitis c for use in resource limited settings |
| topic | Hepatitis C Rapid Diagnostic Test Resource Limited Hepacivirus |
| url | http://hdl.handle.net/11086/556625 |
| work_keys_str_mv | AT leathersjamess validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT pisanomariabelen validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT revivianaelizabeth validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT vanoordg validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT sultana validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT boonstraa validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings AT debesjd validationofapointofcarerapiddiagnostictestforhepatitiscforuseinresourcelimitedsettings |