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PARTICULATE BONE MATRIX USAGE FOR ALVEOLAR BONE CONSERVATION. A HISTOMORPHOMETRIC STUDY.
Different filling materials have been used in an attempt to repair bone loss situations.<br />Objective: The present study aimed to examine the effect of a bone matrix in post-extraction<br />remodelling of the alveolar bone, and to perform a histomorphometric analysis of the<br />...
Different filling materials have been used in an attempt to repair bone loss situations.<br />Objective: The present study aimed to examine the effect of a bone matrix in post-extraction<br />remodelling of the alveolar bone, and to perform a histomorphometric analysis of the<br />residual alveolar ridges in Wistar rats.<br />Material and Methods: Both rat first lower molars were extracted and the right alveoli<br />were filled with particles of a bone matrix with mineral components (MO-UNC) (experimental<br />group, EG). The left alveoli were used as a control group (CG). The animals were<br />sacrificed at 0 hrs, 15, 30 and 60 days after extraction, and the samples were processed.<br />Histological sections were made at the level of the mesial alveolus of the first lower molar.<br />Repair of the alveoli was histologically evaluated and a histomorphometric study of total<br />alveolar volume (TAV), height of the buccal plate (Bh), height of the lingual plate (Lh)<br />and percentage of osseointegration (OI) of the particles was performed to compare the<br />residual ridges of CG with those of the EG. Statistical analysis of the data was performed.<br />Results: In the cases of the experimental group, newly-formed bone tissue was identified<br />around the MO-UNC particles (osseointegration). Histomorphometric data indicate<br />that, at 60 days post-extraction, TAV was significantly greater for EG when compared<br />with CG (p<0.05) and the percentage of osseointegration of the particles increased as a<br />function of time (57.6 %, 90.5% y 95.5%, for EG at 15, 30 y 60 days respectively).<br />Conclusions: The bone matrix (MO-UNC) evaluated in this study is an osteoconductive<br />material that prevents the collapse of post-extraction alveolar bone.
