NAT2 gene diversity and its evolutionary trajectory in the Americas by Bisso Machado, R., Ramallo, Virginia, Paixão Côrtes, V. R., Acuña Alonzo, V., Demarchi, Dario, Sandoval, J. R. S., Granara, A. A. S., Salzano, F. M., Hünemeier, T., Bortolini, M. C.

“…Data from the ~ 44 kb region surrounding NAT2 in 819 individuals from Africa, East-Asia, Europe and America were used in additional analyses. No significant differences in the acetylator NAT2 haplotype and phenotype distributions were found between Native American populations practicing farming and/or herding and those practicing hunting and gathering, probably because of the absence or weakness of selection pressures and presence of demographic and random processes preventing detection of any selection signal.…”
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