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    De Relojes y Ritmos Biológicos by Guido, Mario

    Published 2013
    “…Light is the main synchronizerof central clocks located in the brain through a non-visualcircuit that goes from the retina to the brain. The modern life,artificial light conditions, shift work and trans meridianflights have severely affected the daily activity rhythmcausing the desynchronization of endogenous processes.Moreover, the disruption of circadian rhythmicity isassociated to metabolic and sleep disorders, seasonaldepressions, etc.…”
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