Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model
Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina.
| Main Authors: | , , , , |
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| Format: | conferenceObject |
| Language: | eng |
| Published: |
2023
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| Online Access: | http://hdl.handle.net/11086/548375 |
| _version_ | 1806012142300692480 |
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| author | Romanazzi Chumbita, Lucas Reati, Carolina Fontanetti, Pablo Alejandro Interlandi, Victoria Centeno, Viviana Andrea |
| author_facet | Romanazzi Chumbita, Lucas Reati, Carolina Fontanetti, Pablo Alejandro Interlandi, Victoria Centeno, Viviana Andrea |
| author_sort | Romanazzi Chumbita, Lucas |
| collection | Repositorio Digital Universitario |
| description | Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. |
| format | conferenceObject |
| id | rdu-unc.548375 |
| institution | Universidad Nacional de Cordoba |
| language | eng |
| publishDate | 2023 |
| record_format | dspace |
| spelling | rdu-unc.5483752024-07-02T18:28:13Z Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model Romanazzi Chumbita, Lucas Reati, Carolina Fontanetti, Pablo Alejandro Interlandi, Victoria Centeno, Viviana Andrea Monofluorphosfate Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Reati, Carolina. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Fontanetti, Pablo Alejandro. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Introducción a la Química y Física Biológicas A; Argentina. Fil: Interlandi, Victoria. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Centeno, Viviana Andrea. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Depending on the dose and the way of administration, fluoride (F-) produces different physico-chemicals and biological effects on bone tissue. The F- biodisponibility is higher when it is administrated as sodium monofluorphosphate (MFP) compared to sodium fluoride (NaF) at equivalent doses. OBJECTIVE: to compare the effect produced by F- administratio n in the form of NaF or MFP, post first molar extraction, on biochemicals markers of phosphocalcic metabolism and morphometric parameters of mandibular growth. METHODS: the first right lower molar of twelve 21-days-old male Wistar rats was extracted under anesthesia. Then, rats were divided into three experimental groups which received distilled water (control) or a solution containing 80 mmol of NaF or MFP per day during 21 days. The treatment was administrated by orogastric catheter. After treatment, animals were euthanized by cervical dislocation and mandibles were collected. Plasma Ca and P levels and alkaline phosphatase (ALP) activity were determined. Morphometric parameters of mandible growth were measured on digital radiographic images using the software Romexis. Data were analyzed by ANOVA and Bonferroni?s post hoc test. RESULTS: Phosphatemia increased in animals under F- treatment respect control animals (p<0,05); an increase in ALP activity was observed o nly in NaF group compared to control (p<0,05). The F- treatment, d! id not affect mandible growth parameters. CONCLUSIONS: the administration of F-, as NaF or MFP, by orogastric catheter after first molar extraction, affected some plasma markers related with phosphocalcic metabolism, effect more pronounced in NaF group. Fil: Romanazzi Chumbita, Lucas. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Reati, Carolina. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Fontanetti, Pablo Alejandro. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Introducción a la Química y Física Biológicas A; Argentina. Fil: Interlandi, Victoria. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Fil: Centeno, Viviana Andrea. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Química Biológica A; Argentina. Otras Ciencias de la Salud 2023-08-07T14:06:29Z 2023-08-07T14:06:29Z 2016 conferenceObject http://hdl.handle.net/11086/548375 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ Impreso |
| spellingShingle | Monofluorphosfate Romanazzi Chumbita, Lucas Reati, Carolina Fontanetti, Pablo Alejandro Interlandi, Victoria Centeno, Viviana Andrea Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title | Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title_full | Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title_fullStr | Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title_full_unstemmed | Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title_short | Effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| title_sort | effect of sodium fluoride or sodium monofluorphosphate treatment in an alveolar bone healing experimental model |
| topic | Monofluorphosfate |
| url | http://hdl.handle.net/11086/548375 |
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