Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats
Near-term rat fetuses detect and associate ethanol’s sensory and postabsortive properties. We aimed to evaluate changes upon operant conditioning in neonates, as a function of prenatal ethanol-mediated associative experiences. Prenatal treatments were: Paired group, dams administered (i.g.) with cin...
| Main Authors: | , , |
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| Format: | Online |
| Language: | spa |
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Universidad Nacional de Córdoba
2011
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| Online Access: | https://revistas.unc.edu.ar/index.php/racc/article/view/5224 |
| _version_ | 1811171497811640320 |
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| author | March, Samanta Mabel Abate, Paula Molina, Juan Carlos |
| author_facet | March, Samanta Mabel Abate, Paula Molina, Juan Carlos |
| author_sort | March, Samanta Mabel |
| collection | Portal de Revistas |
| description | Near-term rat fetuses detect and associate ethanol’s sensory and postabsortive properties. We aimed to evaluate changes upon operant conditioning in neonates, as a function of prenatal ethanol-mediated associative experiences. Prenatal treatments were: Paired group, dams administered (i.g.) with cineole and 15-min later with EtOH (2.0 g/kg); Long-delay group, dams received cineole 6 hours before ethanol intoxication; Water group, dams received two administrations of water separated by 15 min. On PD1 neonates were trained in an operant task. Two different learning conditions were used. Paired pups were trained under a FR=1 reinforcement schedule. Yoked pups received the reinforcer but, unrelated to their own behavior. Milk or Cineole-flavored milk were the reinforce solutions. Present results support the idea that ethanol-related prenatal memories modulate operant responsiveness when pups are reexposed to cues that predict toxic consequences of the drug.. |
| format | Online |
| id | oai:ojs.revistas.unc.edu.ar:article-5224 |
| institution | Universidad Nacional de Cordoba |
| language | spa |
| publishDate | 2011 |
| publisher | Universidad Nacional de Córdoba |
| record_format | ojs |
| spelling | oai:ojs.revistas.unc.edu.ar:article-52242019-05-20T15:41:46Z Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats La asociación prenatal entre un taco quimiosensorial (Cineole) y los efectos postabsortivos del etanol modula la respuesta posterior del operador a la leche con sabor a Cineole en ratas de 1 día de edad March, Samanta Mabel Abate, Paula Molina, Juan Carlos aprendizaje fetal etanol reforzamiento condicionamiento Psicobiología fetal learning ethanol reinforcement conditioning Near-term rat fetuses detect and associate ethanol’s sensory and postabsortive properties. We aimed to evaluate changes upon operant conditioning in neonates, as a function of prenatal ethanol-mediated associative experiences. Prenatal treatments were: Paired group, dams administered (i.g.) with cineole and 15-min later with EtOH (2.0 g/kg); Long-delay group, dams received cineole 6 hours before ethanol intoxication; Water group, dams received two administrations of water separated by 15 min. On PD1 neonates were trained in an operant task. Two different learning conditions were used. Paired pups were trained under a FR=1 reinforcement schedule. Yoked pups received the reinforcer but, unrelated to their own behavior. Milk or Cineole-flavored milk were the reinforce solutions. Present results support the idea that ethanol-related prenatal memories modulate operant responsiveness when pups are reexposed to cues that predict toxic consequences of the drug.. Los fetos de rata a término detectan, y asocian entre sí, las propiedades sensoriales y farmacológicas del etanol. En el presente estudio se evaluaron cambios en un aprendizaje operante, en función de las experiencias fetales con etanol. Los tratamientos prenatales fueron: Grupo "Apareado", las hembras fueron administradas con cineol y 15-min después con etanol (2.0 g/kg); Grupo "Larga-Huella", se administró cineol y 6 horas mas tarde, etanol y Grupo "Agua", las hembras recibieron dos administraciones de agua separadas por 15 minutos. Las crías fueron entrenadas en una tarea operante. Se emplearon dos condiciones de aprendizaje (apareado y acoplado). Los sujetos "Apareados" fueron entrenados bajo un esquema de reforzamiento continuo. Los sujetos "Acoplados" recibieron el reforzador de manera independiente de su conducta. Los reforzadores fueron leche o leche saborizada con cineol. Los resultados sugieren que las memorias prenatales relacionadas al alcohol pueden modular las respuestas operantes cuando las crías son re-expuestas a claves predictoras de los efectos tóxicos etílicos. Near-term rat fetuses detect and associate ethanol's sensory and postabsortive properties. We aimed to evaluate changes upon operant conditioning in neonates, as a function of prenatal ethanol-mediated associative experiences. Prenatal treatments were: Paired group, dams administered (i.g.) with cineole and 15-min later with EtOH (2.0 g/kg); Long-delay group, dams received cineole 6 hours before ethanol intoxication; Water group, dams received two administrations of water separated by 15 min. On PD1 neonates were trained in an operant task. Two different learning conditions were used. Paired pups were trained under a FR=1 reinforcement schedule. Yoked pups received the reinforcer but, unrelated to their own behavior. Milk or Cineole-flavored milk were the reinforce solutions. Present results support the idea that ethanol-related prenatal memories modulate operant responsiveness when pups are re-exposed to cues that predict toxic consequences of the drug. Universidad Nacional de Córdoba 2011-07-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unc.edu.ar/index.php/racc/article/view/5224 10.32348/1852.4206.v3.n2.5224 Argentinean Journal of Behavioral Sciences; Vol 3, No 2 (2011): Revista Argentina de Ciencias del Comportamiento; 12-18 Revista Argentina de Ciencias del Comportamiento; Vol 3, No 2 (2011): Revista Argentina de Ciencias del Comportamiento; 12-18 1852-4206 10.32348/1852.4206.v3.n2 spa https://revistas.unc.edu.ar/index.php/racc/article/view/5224/5389 Derechos de autor 2011 Samanta Mabel March, Paula Abate, Juan Carlos Molina |
| spellingShingle | aprendizaje fetal etanol reforzamiento condicionamiento Psicobiología fetal learning ethanol reinforcement conditioning March, Samanta Mabel Abate, Paula Molina, Juan Carlos Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title | Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title_alt | La asociación prenatal entre un taco quimiosensorial (Cineole) y los efectos postabsortivos del etanol modula la respuesta posterior del operador a la leche con sabor a Cineole en ratas de 1 día de edad |
| title_full | Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title_fullStr | Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title_full_unstemmed | Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title_short | Prenatal association between a chemosensory cue (cineole) and ethanol postabsortive effects modulates later operant responsiveness to cineole-flavored milk in 1 day old rats |
| title_sort | prenatal association between a chemosensory cue cineole and ethanol postabsortive effects modulates later operant responsiveness to cineole flavored milk in 1 day old rats |
| topic | aprendizaje fetal etanol reforzamiento condicionamiento Psicobiología fetal learning ethanol reinforcement conditioning |
| topic_facet | aprendizaje fetal etanol reforzamiento condicionamiento Psicobiología fetal learning ethanol reinforcement conditioning |
| url | https://revistas.unc.edu.ar/index.php/racc/article/view/5224 |
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